Title :
Bacteria-based microrobot for chemotaxis delivery of microcubics
Author :
Keon Huh ; Darong Oh ; Hyung Jung Yoo ; Byunghwa Song ; Dong-il Dan Cho ; Jong-Mo Seo ; Sung Jae Kim
Author_Institution :
Dept. of Electr. & Comput. Eng., Seoul Nat. Univ., Seoul, South Korea
Abstract :
We proposed a simple microfluidic device that enabled anisotropic absorption of detoxified S. typhimurium bacteria to each microcubic so that the particles can swim toward desirable direction by chemotaxis of the bacteria. The speed of the “bacteria-based microrobot” was ~5 um/sec which is faster than any prior demonstrations, leading to an effective drug delivery system.
Keywords :
bioMEMS; cell motility; drug delivery systems; microfluidics; microorganisms; anisotropic absorption; bacteria based microrobot; detoxified S. typhimurium bacteria; drug delivery system; microcubic chemotaxis delivery; microfluidic device; polycaprolactone microcubics; Absorption; Chemicals; Microfluidics; Microorganisms; Reservoirs; Scanning electron microscopy; Surface treatment; Microrobot; S. typhimurium; actuator; anisotropic absorption; chemotaxis; microcubics; microfluidics;
Conference_Titel :
Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers - 2015 18th International Conference on
Conference_Location :
Anchorage, AK
DOI :
10.1109/TRANSDUCERS.2015.7180927
