Title :
Optimized modeling of the intra myocardial coronary circulation
Author :
Hirayama, H. ; Okizaki, A. ; Okita, T. ; Nishimura, T.
Author_Institution :
Dept. of Public Health, Asahikawa Med. Coll., Japan
Abstract :
We propose an optimized model of coronary circulation for evaluating patho-physiological hemodynamical changes in the intra myocardial blood flow. The model consisted of an equivalent electrical circuit comprising epicardial, sub-epicardial, the middle layer and the sub endocardial regions. The cost function consisted of squares of the temporal and static changes in perfusion pressures, intra myocardial arterial and venous flow rates and control inputs. We could simulate reported experimental data for coronary arterial and venous flows
Keywords :
biocontrol; blood vessels; cardiovascular system; haemodynamics; optimal control; physiological models; arterial flow rates; cost function; epicardial region; equivalent electrical circuit; intra myocardial blood flow; intra myocardial coronary circulation; middle layer region; optimized modeling; patho-physiological hemodynamical changes; perfusion pressures; static changes; sub endocardial regions; sub-epicardial region; temporal changes; venous flow rates; Biomedical engineering; Blood flow; Circuits; Cities and towns; Educational institutions; Muscles; Myocardium; Optimal control; Pressure control; Public healthcare;
Conference_Titel :
Control Applications, 1999. Proceedings of the 1999 IEEE International Conference on
Conference_Location :
Kohala Coast, HI
Print_ISBN :
0-7803-5446-X
DOI :
10.1109/CCA.1999.801160
