Endothelial cell micro-motion monitored by ECIS during monocytes application

Author

Kataoka, N. ; Iwaki, K. ; Mochizuki, S. ; Ogasawara, Y. ; Tsujioka, K. ; Kajiya, F.

Author_Institution

Dept. of Med. Eng. & Syst. Cardiology, Kawasaki Med. Sch., Okayama, Japan

Volume

1

fYear

1999

fDate

1999

Abstract

We measured the endothelial cell micro-motion by the Electric Cell-substrate Impedance Sensing (ECIS) system during monocyte application. Application of monocytes to the confluent bovine aortic endothelial cell (BAEC) cultured on the electrode caused a slight decrease in the measured electrical resistance compared with the static control BAEC. This means that gaps between cells and/or between cells and substrates became wider. These results imply that the focal adhesion complex and cytoskeletal structure of BAEC change dynamically during monocyte application

Keywords

adhesion; biochemistry; bioelectric phenomena; blood vessels; cellular transport; confluent bovine aortic endothelial cell; cytoskeletal structure; electric cell-substrate impedance sensing; endothelial cell micro-motion; focal adhesion complex structure; gaps between cells; monocytes application; resistance change; Biomedical engineering; Biomedical monitoring; Bovine; Cells (biology); Electric resistance; Electric variables measurement; Electrical resistance measurement; Immune system; Impedance; Laboratories;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.802080

Filename

802080