• DocumentCode
    347016
  • Title

    Modification of evoked responses in cultured cortical networks

  • Author

    Jimbo, Yasuhiko ; Torimitsu, Keiichi

  • Author_Institution
    NTT Basic Res. Labs., Kanagawa, Japan
  • Volume
    1
  • fYear
    1999
  • fDate
    1999
  • Abstract
    Activity-dependent modification of evoked activity was studied using cultured cortical networks on electrode-array substrates. The novel multi-site stimulation system enabled the authors to observe pathway-specific enhancement and depression of network activity simultaneously induced by a single tetanus. Correlation analysis revealed that this bidirectional modification followed a common rule: how closely the individual pathways were correlated with the tetanized pathway
  • Keywords
    bioelectric potentials; biological specimen preparation; brain; neural nets; neurophysiology; bidirectional modification; correlation analysis; electrode-array substrates; network activity depression; pathway-specific enhancement; single tetanus; tetanized pathway; Disk recording; Electrodes; Embryo; Hard disks; Information processing; Intelligent networks; Laboratories; Monitoring; Neural networks; Neurons;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    [Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
  • Conference_Location
    Atlanta, GA
  • ISSN
    1094-687X
  • Print_ISBN
    0-7803-5674-8
  • Type

    conf

  • DOI
    10.1109/IEMBS.1999.802448
  • Filename
    802448