Title :
Simulation of dendritic structure of pyramidal cells in the cerebral cortex
Author :
Togawa, T. ; Otsuka, K.
Author_Institution :
Inst. of Biomater. & Bioeng., Tokyo Med. & Dental Univ., Japan
Abstract :
The authors proposed a model of cortical neural network structure based on the single-cell representation hypothesis and showed that the relation between surface area and thickness of the cortex can be explained consistently (T. Togawa and K. Otsuka, 1980). This study is an attempt of simulating dendritic structure of the neuron in the cortex assuming the total length of a dendrite is proportional to the number of synapses on it. Obtained dendritic structure was compared with the actual morphological structure in animals of different sizes. The apparent similarity of the actual and the simulated dendritic structures suggests the consistency of the proposed model
Keywords :
brain models; cellular biophysics; neurophysiology; actual morphological structure; cerebral cortex; dendrite total length; dendritic structure simulation; different sized animals; proposed model consistency; pyramidal cells; synapses number; Animal structures; Biological neural networks; Brain modeling; Cerebral cortex; Humans; Mice; Neurons;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802479
