Title :
An investigation of N-let summation mechanisms in muscle
Author :
Dorgan, Stephen J.
Author_Institution :
Inst. of Autom. Control Eng., Tech. Univ. of Munich, Germany
Abstract :
The dynamics responsible for non-linear (N-let) force summation effects in mammalian skeletal muscle are investigated. These investigations are performed using a recently developed physiologically based mathematical model for skeletal muscle. Simulation results are compared to both internal and external experimental data from isolated muscles and muscle fibres. The results indicate that a subtle interplay between the Ca2+ release and contraction dynamics of muscle may be responsible for N-let summation effects
Keywords :
biocontrol; biomechanics; force control; muscle; nonlinear dynamical systems; physiological models; Ca2+ release; FNS; N-let control strategies; N-let summation mechanisms; complex I/O dynamics; contraction dynamics; external data; internal data; isolated muscles; mammalian skeletal muscle; muscle fibres; muscle force generation; nonlinear force summation effects; physiologically based mathematical model; rabbit muscle; Automatic control; Fatigue; Force control; Immune system; Mathematical model; Muscles; Nonlinear dynamical systems; Predictive models; Pulse generation; Strontium;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802631
