Title :
Focusing approach using LD block and association study with haplotype combination on DNA data
Author_Institution :
Clinical Res. Center, Med. Hosp. of Tokyo Med. & Dental Univ., Tokyo, Japan
Abstract :
In statistical genetics, SNPs, haplotype and diplotype are the major polymorphic markers in DNA data. Therefore, over approximately the last 10 years, the relative frequencies of different haplotypes have been estimated, their structures have been examined, and haplotypes have been used for association studies. We focus haplotype analyses, e.g., identification of haplotype blocks and haplotype association studies.
Keywords :
DNA; biology computing; data analysis; genetics; molecular biophysics; statistical analysis; DNA data; LD block; SNP; diplotype; haplotype analyses; haplotype association study; haplotype blocks; haplotype combination; polymorphic markers; statistical genetics; Algorithm design and analysis; Biological cells; Couplings; DNA; Estimation; Spatial databases; DNA marker; SNPs data; association study; haplotype; maximum likelihood estimation;
Conference_Titel :
ICT and Knowledge Engineering (ICT&KE), 2013 11th International Conference on
Conference_Location :
Bangkok
Print_ISBN :
978-1-4799-2294-9
DOI :
10.1109/ICTKE.2013.6756266