DocumentCode
3483713
Title
Biosensors for continuous in vivo glucose monitoring
Author
Claremont, Denzil J. ; Shaw, Gill W. ; Pickup, John C.
Author_Institution
Guy´´s Hospital, London, UK
fYear
1988
fDate
4-7 Nov. 1988
Firstpage
740
Abstract
The authors have developed a ferrocene-mediated amperometric glucose oxidase enzyme electrode for continuous in vivo measurement of subcutaneous tissue glucose in man. This sensor can be used to detect hypoglycemia. In vitro studies have shown that the response time of the sensor is less than one minute and probably does not contribute significantly to the observed phase lag between the nadir for the blood and subcutaneous glucose. In the subjects studied to date, the mean delay was about 3 min, but the range was 0-15 minutes.<>
Keywords
biomedical equipment; patient monitoring; 0 to 15 min; biosensors; continuous in vivo glucose monitoring; ferrocene-mediated amperometric glucose oxidase enzyme electrode; hypoglycemia detection; phase lag; sensor response time; subcutaneous tissue glucose;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location
New Orleans, LA, USA
Print_ISBN
0-7803-0785-2
Type
conf
DOI
10.1109/IEMBS.1988.94988
Filename
94988
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