Title :
The effect of shear-induced lift force on the high-speed cell motion in microchannel with adhesive wall
Author :
Morimoto, Kenichi ; Rangsiwatakapong, D. ; Suzuki, Yuya
Author_Institution :
Dept. of Mech. Eng., Univ. of Tokyo, Tokyo, Japan
Abstract :
For high-speed adhesion-based cell separation, we propose a new cell-motion model including the shear-induced lift force, with which the cell motion at high flow velocities can be analyzed. Also, we have developed a novel sub-micron-accuracy measurement method of the three-dimensional position of cells. We have clarified the effect of the shear-induced lift force on the cell motion near adhesive walls for the first time.
Keywords :
adhesion; bioMEMS; cell motility; flow separation; microchannel flow; shear flow; adhesive wall; flow velocity; high-speed adhesion-based cell separation; high-speed cell motion; microchannel; shear-induced lift force effect; submicron-accuracy measurement; three-dimensional cell position; Adhesives; Atmospheric measurements; Data models; Force; Microchannel; Numerical models; Predictive models;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
Conference_Location :
Taipei
Print_ISBN :
978-1-4673-5654-1
DOI :
10.1109/MEMSYS.2013.6474197