Title :
Labs on chips for biomedical applications
Author :
van den Berg, A.
Author_Institution :
BIOS/Lab.-on-a-Chip Group, Univ. of Twente, Enschede, Netherlands
Abstract :
Lab on Chip devices have a great potential for medical applications as illustrated in three examples. First, a disposable, prefilled capillary electrophoresis chip for monitoring lithium in blood of manic depressive patients is discussed. In a second example, we present a simple chip for counting sperm cells in semen is presented that is used to determine male fertility. Finally, we present the realization of a blood-brain barrier on chip that establishes a versatile platform for drug screening and has the potential to greatly reduce and replace animal testing.
Keywords :
biomedical equipment; blood; brain; capillarity; cellular biophysics; drugs; electrophoresis; lab-on-a-chip; animal testing; biomedical applications; blood-brain barrier; disposable-prefilled capillary electrophoresis chip; drug screening; lab-on-chip devices; male fertility; manic depressive patients; semen; sperm cell counting; Biological system modeling; Blood; Drugs; Electrodes; Lithium; Microfluidics; Semiconductor device measurement;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
Conference_Location :
Taipei
Print_ISBN :
978-1-4673-5654-1
DOI :
10.1109/MEMSYS.2013.6474199