DocumentCode :
3499476
Title :
Microfluidic device with carbon nanotube channel walls for blood plasma extraction
Author :
Yin-Ting Yeh ; Perea-Lopez, N. ; Dasgupta, Avirup ; Harouaka, R. ; Terrones, M. ; Si-Yang Zheng
Author_Institution :
Dept. of Bioeng., Pennsylvania State Univ., University Park, PA, USA
fYear :
2013
fDate :
20-24 Jan. 2013
Firstpage :
951
Lastpage :
954
Abstract :
The human plasma biomarker analysis is promised to be a revolution for disease diagnosis and therapeutic monitoring, but it also presents major technical challenges that needs to be addressed [1]. Plasma extract from whole blood is the first step for plasma biomarker analysis. This paper reports a new microfluidic device with channel walls made of nitrogen-doped carbon nanotubes (CNxCNT) as a point-of-care device to continuously extract plasma from human whole blood. The cross flow microfiltration principle is applied in this plasma extraction device. The blood sample is transported within the double spiral channels. The plasma diffuses through the porous CNxCNT wall into the spiral plasma channel while blood cells continue to flow inside the spiral blood sample channel [2].
Keywords :
bioMEMS; biodiffusion; blood; carbon nanotubes; cellular biophysics; diseases; microfluidics; nanomedicine; nitrogen; C:N; blood plasma extraction device; carbon nanotube channel walls; cross flow microfiltration principle; disease diagnosis; double spiral channels; human plasma biomarker analysis; microfluidic device; nitrogen-doped carbon nanotubes; plasma diffusion; point-of-care device; therapeutic monitoring; Blood; Cells (biology); Filtration; Fluorescence; Microfluidics; Plasmas; Spirals;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
Conference_Location :
Taipei
ISSN :
1084-6999
Print_ISBN :
978-1-4673-5654-1
Type :
conf
DOI :
10.1109/MEMSYS.2013.6474403
Filename :
6474403
Link To Document :
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