Title :
Spira Mirabilis enhanced density gradient centrifguation
Author :
Kearney, S.M. ; Kinahan, D.J. ; Ducree, J.
Author_Institution :
Nat. Centre for Sensor Res., Dublin City Univ., Dublin, Ireland
Abstract :
The centrifugal microfluidic “lab-on-a-disc” paradigm is particularly suited to the pre-conditioning of whole blood. In this work we define the geometry of sedimentation chambers using the Spira Mirabilis (equiangular spiral) and so enhance the Boycott Effect and increase the speed at which blood may be stratified using a density gradient media. We find that using the Spira Mirabilis defined chambers can increase the speed of stratification by up to 25% compared with equivalent linear chambers.
Keywords :
bioMEMS; blood; lab-on-a-chip; microfluidics; sedimentation; Spira Mirabilis defined chambers; Spira Mirabilis enhanced density gradient centrifguation; blood preconditioning; boycott effect; centrifugal microfluidic lab-on-a-disc paradigm; density gradient media; equiangular spiral; sedimentation chambers; Blood; Educational institutions; Media; Microfluidics; Rotation measurement; Sediments; Spirals;
Conference_Titel :
Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
Conference_Location :
Taipei
Print_ISBN :
978-1-4673-5654-1
DOI :
10.1109/MEMSYS.2013.6474427
