• DocumentCode
    3500512
  • Title

    Flip-drop: Droplet array created by surface energy trap for combinatorial screening

  • Author

    Yi Zhang ; Tza-Huei Wang

  • fYear
    2013
  • fDate
    20-24 Jan. 2013
  • Firstpage
    1149
  • Lastpage
    1152
  • Abstract
    Here we present a droplet array platform named "flip-drop" that incorporates novel surface energy traps (SETs) to generate an array of droplets of combinatorial mixtures for bioanalytical screening. This droplet array platform is exemplified using a quantum-dot fluorescence resonance energy transfer (QD-FRET) sensing assay for detection of the RSF1 cancer biomarker.
  • Keywords
    biological techniques; biomedical transducers; cancer; drops; quantum dots; sensor arrays; surface energy; QD-FRET; RSF1 cancer biomarker detection; SET; bioanalytical screening; combinatorial mixture screening; droplet array platform generation; flip-drop; quantum-dot fluorescence resonance energy transfer sensing assay; surface energy trap; Arrays; Cancer; DNA; Fluorescence; Quantum dots; Sensors; Surface treatment;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro Electro Mechanical Systems (MEMS), 2013 IEEE 26th International Conference on
  • Conference_Location
    Taipei
  • ISSN
    1084-6999
  • Print_ISBN
    978-1-4673-5654-1
  • Type

    conf

  • DOI
    10.1109/MEMSYS.2013.6474454
  • Filename
    6474454