DocumentCode :
3508976
Title :
Recognition Essential Protein Based on Multi Parameters Combination
Author :
Huang, Haibin ; Wang, Jianxin ; Peng, Jiayang
Author_Institution :
Sch. of Inf. Sci. & Eng., Central South Univ., Changsha
Volume :
3
fYear :
2009
fDate :
7-8 March 2009
Firstpage :
861
Lastpage :
866
Abstract :
For the low recognition degree of essential protein based on topological parameter, the correlation between the essentiality of proteins and their main topological parameters is analyzed and the nature of the essentiality-judgment ability of the parameters is explored firstly. Then, the mutual information of essential node these parameters contain is brought out in virtue of their correlation, based on which the construction method of combined parameter is put forwards. In deeper study, the recognition degree of a combined parameter is found to have close relations not only to the performances of the independent parameters it constructed from, but also to the correlation between these independent parameters, and a asynchronous algorithm based on parameters combination is proposed lastly. The results of the emulation are not only consistent to each other highly, but also show that the performance of the method is better than that of the others obviously.
Keywords :
biology computing; macromolecules; proteins; asynchronous algorithm; essential protein; essentiality-judgment ability; multiparameters combination; recognition degree; Computer science; Computer science education; Educational technology; Emulation; Fungi; Information analysis; Information science; Mutual information; Performance evaluation; Protein engineering; Combined parameter; essential node; identification; protein network; topological structure;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Education Technology and Computer Science, 2009. ETCS '09. First International Workshop on
Conference_Location :
Wuhan, Hubei
Print_ISBN :
978-1-4244-3581-4
Type :
conf
DOI :
10.1109/ETCS.2009.729
Filename :
4959445
Link To Document :
بازگشت