Title :
Finite element bidomain calculations
Author :
Sepulveda, Nestor G. ; Roth, Bradley J. ; Wikswo, John P., Jr.
Author_Institution :
Vanderbilt Univ., Nashville, TN, USA
Abstract :
The finite-element method is used to study the electrical response of a 2-D bidomain model of cardiac tissue to current injection. For unequal anisotropy ratios of the intracellular and extracellular spaces, injection of current into the tissue induces a transmembrane potential that has a complicated spatial dependence, including adjacent regions of depolarized and hyperpolarized tissue. This behavior could have implications for the electrical stimulation of the tissue, for defibrillation, and in the study of the virtual cathode effect.<>
Keywords :
bioelectric potentials; biomembrane transport; cardiology; cellular transport and dynamics; finite element analysis; muscle; physiological models; 2-D bidomain model; 2D model; cardiac muscle; cardiac tissue; current injection; defibrillation; depolarized tissue; electrical response; electrical stimulation; extracellular spaces; finite-element method; hyperpolarized tissue; intracellular spaces; spatial dependence; transmembrane potential; unequal anisotropy ratios; virtual cathode effect;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.95273
