Title :
Multiple automatic and nonautomatic stable states in excitable cardiac cells
Author :
Landau, Mayer ; Lorente, Paco ; Henry, Jacques
Author_Institution :
INSERM, Paris, France
Abstract :
The authors have used continuation-bifurcation techniques to explore phase transitions between automaticity and nonautomaticity in cardiac pacemaker cells. From the findings, they were able to describe the entire behavior of a single element and to define bistabilities and hysteresis patterns around two Hopf bifurcation points. Computation of attractor basins delineated the topological conditions allowing the cell to pass from one state to another as a result of brief perturbing impulses.<>
Keywords :
biocontrol; cardiology; cellular biophysics; neurophysiology; physiological models; Hopf bifurcation points; attractor basins; automaticity; bistabilities; brief perturbing impulses; cardiac pacemaker cells; continuation-bifurcation techniques; excitable cardiac cells; hysteresis patterns; multiple automatic stable states; nonautomatic stable states; nonautomaticity; phase transitions; single element; topological conditions;
Conference_Titel :
Engineering in Medicine and Biology Society, 1988. Proceedings of the Annual International Conference of the IEEE
Conference_Location :
New Orleans, LA, USA
Print_ISBN :
0-7803-0785-2
DOI :
10.1109/IEMBS.1988.95278
