• DocumentCode
    3521876
  • Title

    A Method for Improving the Accuracy of Predicting Protein Structural Classes

  • Author

    Wang, Tong ; Wang, Anbao ; Hu, Lihua

  • Author_Institution
    Inst. of Comput. & Inf., Shanghai Second Polytech. Univ., Shanghai, China
  • fYear
    2011
  • fDate
    28-29 May 2011
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    The structure of a protein is closely correlated to its function. Feature dimension reduction method is one of most famous machine learning tools. Some researchers have begun to explore feature dimension reduction method for computer vision problems. Few such attempts have been made for classification of high-dimensional protein data sets. In this paper, feature dimension reduction method is employed to reduce the size of the features space. Comparison between linear Feature dimension reduction method and nonlinear feature dimension reduction method is performed to predict protein structural classes. The results with high success rates indicate that the above method is used effectively to deal with this complicated problem of predicting proteins structural classes.
  • Keywords
    bioinformatics; data reduction; learning (artificial intelligence); molecular configurations; proteomics; feature space size reduction; high dimensional protein data set classification; linear feature dimension reduction method; machine learning tools; nonlinear feature dimension reduction method; protein function; protein structural class prediction; protein structure; Accuracy; Amino acids; Covariance matrix; Kernel; Prediction algorithms; Principal component analysis; Proteins;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Intelligent Systems and Applications (ISA), 2011 3rd International Workshop on
  • Conference_Location
    Wuhan
  • Print_ISBN
    978-1-4244-9855-0
  • Electronic_ISBN
    978-1-4244-9857-4
  • Type

    conf

  • DOI
    10.1109/ISA.2011.5873418
  • Filename
    5873418