DocumentCode :
3530278
Title :
Phase-contrast tomosynthetic experiment on biological samples with synchrotron radiation
Author :
Zhang, Li ; Jin, MingLi ; Huang, Zhifeng ; Xiao, Yongshun ; Yin, Hongxia ; Wang, Zhenchang ; Xiao, Tiqiao
Author_Institution :
Dept. of Eng. Phys., Tsinghua Univ., Beijing, China
fYear :
2010
fDate :
Oct. 30 2010-Nov. 6 2010
Firstpage :
1619
Lastpage :
1621
Abstract :
Tomosynthesis is one of three-dimensional imaging techniques that can remove the effect of overlapping phenomena in radiography, except for computed tomography (CT). In general, CT needs at least hundreds of projections to reconstruct every cross-sectional slice of the samples accurately, while tomosynthesis just requires dozens of projections to reconstruct a series of tomosynthetic slices approximately, Conventional tomosynthesis based on attenuation contrast shows poor results when imaging weakly-absorption objects such as biological samples. In this paper, we present a new type of tomosynthesis, named phase contrast tomosynthesis, combining X-ray phase-contrast imaging mechanism and tomosynthesis, which can obtain higher resolution and image quality for the biological samples with fewer radiation doses and avoid overlapping phenomena. A phase contrast tomosynthetic experiment on a guinea pig cochlea at the Shanghai Synchrotron Radiation Facility (SSRF) was done to evaluate the performances of various reconstruction algorithms integrated with the in-line phase retrieval method.
Keywords :
computerised tomography; diagnostic radiography; dosimetry; image reconstruction; medical image processing; synchrotron radiation; Shanghai synchrotron radiation facility; X-ray phase-contrast imaging mechanism; biological samples; computed tomography; conventional tomosynthesis; guinea pig cochlea; in-line phase retrieval method; phase contrast tomosynthesis; phase contrast tomosynthetic experiment; phase-contrast tomosynthetic experiment; radiation doses; reconstruction algorithms; synchrotron radiation; Biology; Computed tomography; Image reconstruction; Subspace constraints; Synchrotron radiation; X-ray imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Nuclear Science Symposium Conference Record (NSS/MIC), 2010 IEEE
Conference_Location :
Knoxville, TN
ISSN :
1095-7863
Print_ISBN :
978-1-4244-9106-3
Type :
conf
DOI :
10.1109/NSSMIC.2010.5874050
Filename :
5874050
Link To Document :
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