Quantitative beat-to-beat analysis of heart rate dynamics during dipyridamole echocardiographic test [ECG analysis]

Author

Marciano, F. ; Petretta, M. ; Bonaduce, D. ; Migaux, M.L. ; Spinelli, L. ; Ianniciello, A. ; Apicella, C.

Author_Institution

Ist. di Cibernetica, CNR, Napoli, Italy

fYear

1997

fDate

7-10 Sep 1997

Firstpage

399

Lastpage

402

Abstract

The authors measured heart rate variability (HRV) during dipyridamole test (DET) in 36 patients with suspected coronary artery disease (CAD) who underwent coronary angiography for chest pain evaluation. The authors considered Group A: no CAD and negative DET results; Group B: CAD and negative DET; Group C: CAD and positive DET. After dipyridamole, in Group B and C, HRV measures of cardiac vagal control decreased and sympathetic activity increased; differently, in Group A all components of HRV decreased. Therefore, in CAD patients dipyridamole infusion induced a parasympathetic withdrawal with sympathetic predominance despite a negative DET. HRV analysis seems to be able to detect this autonomic disturbance, improving the diagnostic accuracy of DET in patients with suspected CAD

Keywords

echocardiography; electrocardiography; medical signal processing; ECG analysis; autonomic disturbance; cardiac vagal control; chest pain evaluation; coronary angiography; diagnostic accuracy improvement; dipyridamole echocardiographic test; heart rate dynamics; parasympathetic withdrawal; quantitative beat-to-beat analysis; suspected coronary artery disease patients; sympathetic predominance; Angiography; Cardiac disease; Cardiovascular diseases; Coronary arteriosclerosis; Heart rate; Heart rate variability; Medical tests; Pain; Patient monitoring; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 1997

Conference_Location

Lund

ISSN

0276-6547

Print_ISBN

0-7803-4445-6

Type

conf

DOI

10.1109/CIC.1997.647917

Filename

647917