Title :
A digital CMOS DNA chip
Author :
Frey, Alexander ; Schienle, Meinrad ; Paulus, Christian ; Jun, Zou ; Hofmann, Franz ; Schindler-Bauer, Petra ; Holzapfl, Birgit ; Atzesberger, Melanie ; Beer, Gottfried ; Fritz, Michaela ; Haneder, Thomas ; Hanke, Hans-Christian ; Thewes, Roland
Author_Institution :
Infineon Technol. AG, Munich, Germany
Abstract :
A fully electronic medium density DNA micro array is presented using a CMOS process extended by gold electrodes. The chip provides 128 sensor sites, in-sensor site current-mode A/D conversion, peripheral circuitry including bandgap and current references, D/A-converters to provide electrode bias voltages, calibration circuitry, and a 6 pin interface for power supply and serial digital data transfer.
Keywords :
CMOS digital integrated circuits; DNA; analogue-digital conversion; biosensors; calibration; current-mode circuits; data communication; digital-analogue conversion; D/A-converters; DNA sensor arrays; bandgap reference; calibration circuitry; current reference; current-mode A/D conversion; digital CMOS DNA chip; electrode bias voltages; gold electrodes; medium density DNA micro array; peripheral circuitry; power supply; serial digital data transfer; Calibration; Chemical sensors; Circuits; Consumer electronics; DNA; Electrodes; Gold; Resistors; Sensor arrays; Voltage;
Conference_Titel :
Circuits and Systems, 2005. ISCAS 2005. IEEE International Symposium on
Print_ISBN :
0-7803-8834-8
DOI :
10.1109/ISCAS.2005.1465237
