Guest Editorial—Special Issue on Synthetic Biology

The 10 papers in this special section on synthetic biology bring together information that both reviews and presents original work aimed at addressing these challenges. These papers incorporate advances and insights from analog circuit design, control theory, RNA-focused circuits; from the control and simulation of stochastics (noise) in living cells and their impact on signal detection; from the fast simulation of stochastic and deterministic bio-molecular differential equations via analog and mixed-signal subthreshold circuits; and from mathematical design techniques for synthetic biology.