Preliminary design towards a magnetic actuated drug delivery system

Targeted drug delivery is playing an important role in the modern medicine due to the potential of delivery effectiveness and minimally invasive procedures. We report a preliminary design of electromagnetic actuation (EMA) system consisting of Helmoholz coil pairs and Maxwell coil pairs for targeted drug delivery and potentially drug release rate control. Preliminary testing indicates that the system is able to effectively move and align the magnetic particles to the desired position and direction within the region of interest. Calcium alginate microcapsules containing iron particles are used for the preliminary tests. One novel design of thermal sensitive and magneto-responsive microcapsule that is responsive to the EMA system is illustrated.