Rapid prototyping of multilayer thermoplastic microfluidic chip

Thermoplastic is a common material in industrial products and it can be applied to microfluidic application since it is much more affordable and stable than PDMS in vary aspects. Based on former studies, a manufacturing process of thermoplastic microfluidic system is proposed, from the feature design to the final microfluidic device. The protocol being proposed is able to achieve rapid prototyping of multilayer thermoplastic microfluidic chips, improve the study efficiency of functional microfluidic product, shorten the period from laboratory to market as well as provide an alternative option for further developing microfluidic commercial products.