• DocumentCode
    3726239
  • Title

    Seeing an explosive way of NSF/SNAP-mediated SNARE-complex disassembly using single-molecule measurements

  • Author

    Je-Kyung Ryu;Duyoung Min;Sang-Hyun Rah;Haesoo Kim;Reinhard Jahn;Tae-Young Yoon

  • Author_Institution
    National Creative Research Initiative Center for Single-Molecule Systems Biology, KAIST, Daejeon 305-701, South Korea
  • Volume
    4
  • fYear
    2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    N-ethylmaleimide-sensitive factor (NSF) and alpha soluble NSF attachment protein (α-SNAP) disassemble the SNAP receptor (SNARE) complex for recycling of the SNARE proteins. Using single-molecule fluorescence and force spectroscopy, we found that NSF appears to use a "spring-loaded" mechanism.
  • Keywords
    "Proteins","Fluorescence","Yttrium","Substrates","Microscopy","Magnetic separation","Magnetic resonance imaging"
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics Pacific Rim (CLEO-PR), 2015 11th Conference on
  • Type

    conf

  • DOI
    10.1109/CLEOPR.2015.7376355
  • Filename
    7376355
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3726239