Title :
Subsurface ablation of biological materials by ultra-short laser pulses
Author :
Smith, N.I. ; Fujita, K. ; Nakamura, O. ; Kawata, S. ; Takamatsu, T.
Author_Institution :
Dept. of Appl. Phys., Osaka Univ., Japan
Abstract :
Submicron sized damage spots were created inside collagen gel by multiphoton absorption of ultra-short 775 nm laser pulses. Submicron nodules were formed both near the surface and at a depth of up to 30 /spl mu/m to test the behaviour and depth-dependence of the damage threshold.
Keywords :
biological effects of laser radiation; laser applications in medicine; proteins; two-photon processes; 775 nm; biological materials; collagen gel; damage localisation; damage threshold; depth-dependence; fluorescent dyes addition; focal depth; laser-induced damage effects; multiphoton absorption; number of pulses; reflection confocal image; submicron sized damage spots; subsurface ablation; total exposure time; two-photon absorption; ultrashort laser pulses; Absorption; Biological materials; Biomedical optical imaging; Electric breakdown; Fluorescence; Laser ablation; Laser theory; Microscopy; Optical pulses; Power lasers;
Conference_Titel :
Lasers and Electro-Optics, 2001. CLEO/Pacific Rim 2001. The 4th Pacific Rim Conference on
Conference_Location :
Chiba, Japan
Print_ISBN :
0-7803-6738-3
DOI :
10.1109/CLEOPR.2001.967811
