Aggregation of red cells and linear velocity gradients: influence on the correlation-based method for quantitative IVUS blood flow at 20 MHz

Author

Lupotti, F.A. ; Zimmer, A. ; Daronat, M. ; Foster, F.S. ; van der Steen, A.F.W. ; Cloutier, G.

Author_Institution

Thoraxcenter, Erasmus MC, Rotterdam, Netherlands

Volume

2

fYear

2002

fDate

8-11 Oct. 2002

Firstpage

1535

Abstract

Recent computer simulations suggest that the presence of aggregates of red blood cells (RBCs), at random angles and lengths, does not affect the measurements of transverse blood flow using a correlation-based method and an IVUS array catheter. Blood velocity gradients were also shown not to influence the correlation-based method for blood velocity estimation. The objective of this study is to quantify the influence of aggregates of RBCs and blood velocity gradients on the correlation-based method during in vitro experiments. For this purpose, measurements were performed on normal and diseased human blood. The decorrelation pattern of a circular ultrasound transducer as a function of transverse blood flow was studied using a Couette system. Agreements were found between the auto-convolution of the acoustical beam and the RF decorrelation patterns.

Keywords

aggregation; biomedical ultrasonics; blood flow measurement; decorrelation; ultrasonic measurement; ultrasonic transducers; velocity measurement; 20 MHz; Couette system; blood velocity gradients; circular ultrasound transducer; correlation-based method; decorrelation pattern; diseased human blood; linear velocity gradients; normal human blood; quantitative IVUS blood flow; random angles; random lengths; red cells aggregation; transverse blood flow; Aggregates; Blood flow; Catheters; Cells (biology); Computer simulation; Decorrelation; Fluid flow measurement; In vitro; Length measurement; Red blood cells;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 2002. Proceedings. 2002 IEEE

ISSN

1051-0117

Print_ISBN

0-7803-7582-3

Type

conf

DOI

10.1109/ULTSYM.2002.1192588

Filename

1192588