• DocumentCode
    419342
  • Title

    Inferring genetic networks from microarray data

  • Author

    Martin, Shawn ; Davidson, George ; May, Elebeoba ; Faulon, Jean-Loup ; Werner-Washburne, Margaret

  • Author_Institution
    Comput. Biol., Sandia Nat. Labs., Albuquerque, NM, USA
  • fYear
    2004
  • fDate
    16-19 Aug. 2004
  • Firstpage
    566
  • Lastpage
    569
  • Abstract
    In theory, it should be possible to infer realistic genetic networks from time series microarray data. In practice, however, network discovery has proved problematic. The three major challenges are 1) inferring the network; 2) estimating the stability of the inferred network; and 3) making the network visually accessible to the user. Here we describe a method, tested on publicly available time series microarray data, which addresses these concerns.
  • Keywords
    biology computing; genetics; inference mechanisms; time series; genetic networks; inference; network discovery; time series microarray data; Bioinformatics; Clustering algorithms; Computational biology; Genetics; Inference algorithms; Laboratories; Logic; Partitioning algorithms; Stability; Testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computational Systems Bioinformatics Conference, 2004. CSB 2004. Proceedings. 2004 IEEE
  • Print_ISBN
    0-7695-2194-0
  • Type

    conf

  • DOI
    10.1109/CSB.2004.1332498
  • Filename
    1332498