DocumentCode
419342
Title
Inferring genetic networks from microarray data
Author
Martin, Shawn ; Davidson, George ; May, Elebeoba ; Faulon, Jean-Loup ; Werner-Washburne, Margaret
Author_Institution
Comput. Biol., Sandia Nat. Labs., Albuquerque, NM, USA
fYear
2004
fDate
16-19 Aug. 2004
Firstpage
566
Lastpage
569
Abstract
In theory, it should be possible to infer realistic genetic networks from time series microarray data. In practice, however, network discovery has proved problematic. The three major challenges are 1) inferring the network; 2) estimating the stability of the inferred network; and 3) making the network visually accessible to the user. Here we describe a method, tested on publicly available time series microarray data, which addresses these concerns.
Keywords
biology computing; genetics; inference mechanisms; time series; genetic networks; inference; network discovery; time series microarray data; Bioinformatics; Clustering algorithms; Computational biology; Genetics; Inference algorithms; Laboratories; Logic; Partitioning algorithms; Stability; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Systems Bioinformatics Conference, 2004. CSB 2004. Proceedings. 2004 IEEE
Print_ISBN
0-7695-2194-0
Type
conf
DOI
10.1109/CSB.2004.1332498
Filename
1332498
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