From passive to active subretinal implants, serving as adapting electronic substitution of degenerated photoreceptors

Author

Zrenner, E. ; Gabel, V.P. ; Gekeler, F. ; Graf, H.G. ; Gruber, H. ; Hämmerle, H. ; Kohler, Klaus ; Nisch, W. ; Sachs, H. ; Saile, H. ; Shinoda, K. ; Stett, A. ; Wilhelm, B.

Author_Institution

Dept. II, Univ. Eye Hospital, Teubingen, Germany

Volume

1

fYear

2004

fDate

25-29 July 2004

Abstract

Utilising differential amplifiers for the adaptation of subretinal implants allows sufficient spatial resolution at varying ambient light surroundings in a grid of 70 μm, as defined by physiological in vitro experiments. It has been shown that an implant can be created that can be positioned in the subretinal space. Electronic circuits have been imprinted underneath each pixel that receives their external energy by subretinal foil-bound wires. Biocompatibility and biostability tests as well as successful surgical procedures have prepared the ground for clinical study in blind RP patients.

Keywords

artificial organs; eye; surgery; vision defects; active subretinal implants; biocompatibility test; biostability test; biostability tests; degenerated photoreceptors; differential amplifiers; electronic circuits; spatial resolution; subretinal foil-bound wires; subretinal implants; Biomedical measurements; Hospitals; Implants; In vitro; Neurons; Performance evaluation; Photoreceptors; Retina; Surgery; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Networks, 2004. Proceedings. 2004 IEEE International Joint Conference on

ISSN

1098-7576

Print_ISBN

0-7803-8359-1

Type

conf

DOI

10.1109/IJCNN.2004.1379977

Filename

1379977