Sencil™ project: development of a percutaneous optical biosensor

Author

Liao, Kuo Chih ; Richmond, F.J. ; Hogen-Esch, Thieo ; Marcu, Laura ; Loeb, Gerald E.

Author_Institution

Alfred E. Mann Inst. for Biomedical Eng., Southern California Univ., CA, USA

Volume

1

fYear

2004

fDate

1-5 Sept. 2004

Firstpage

2082

Lastpage

2085

Abstract

We describe the design, fabrication method, biocompatibility test results, and first application of the novel chemical sensor technology that is under development. The sensor is designed to be minimally invasive, disposable and easily readable to make frequent measurements of various analytes in vivo over a period of 1-3 months. It uses photonic sensing of a chemical reaction that occurs in a polymer matrix bound to the internal end of a chronically implanted percutaneous optical fiber.

Keywords

biochemistry; biomedical equipment; chemical sensors; optical fibres; polymers; skin; 1 to 3 month; Sencil; biocompatibility; chemical reaction; chemical sensor; chronically implanted percutaneous optical fiber; percutaneous optical biosensor; photonic sensing; polymer matrix; Biomedical optical imaging; Biosensors; Chemical and biological sensors; Chemical sensors; Chemical technology; Design methodology; Minimally invasive surgery; Optical device fabrication; Optical sensors; Testing; Optical fiber; Quantum dots; chemical sensor; florescence resonance energy transfer; glucose;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE

Conference_Location

San Francisco, CA

Print_ISBN

0-7803-8439-3

Type

conf

DOI

10.1109/IEMBS.2004.1403612

Filename

1403612