• DocumentCode
    438106
  • Title

    The RatCAP conscious small animal PET tomograph

  • Author

    Woody, C. ; Dzhordzhadze, V. ; Fontaine, R. ; Junnakar, S. ; Kandasamy, A. ; Kriplani, A. ; Krishnamoorthy, S. ; Lecomte, R. ; Connor, P.O. ; Page, C. ; Pratte, J.-F. ; Purschke, M. ; Radeka, V. ; Rampil, I. ; Schlyer, D. ; Shokouhi, S. ; Southekal, S. ;

  • Author_Institution
    Brookhaven Nat. Lab., Upton, NY, USA
  • Volume
    4
  • fYear
    2004
  • fDate
    16-22 Oct. 2004
  • Firstpage
    2334
  • Abstract
    The RatCAP is a small, head mounted PET tomograph being designed and built to image the brain of an awake rat. It will allow PET imaging studies to be carried out on la bora ton rats without the use of anesthesia, which severely suppresses brain functions and affects many of the neurological activities that one would like to study using PET. In addition, it will allow the study of animal behavior while simultaneously acquiring PET data. The tomograph consists of a 4 cm diameter ring containing 12 block detectors, each of which is comprised of a 4×8 array of 2.2×2.2×5 mm3 LSO crystals read out with a matching APD array. The APDs are read out using a custom designed ASIC and VME readout system. Most of the detector components for the RatCAP have been received and the final detector is now under construction. This paper summarizes the status of the project and gives results on detector component testing and performance, development of the readout system, results on image reconstruction, and studies on animal behavior while wearing the ring.
  • Keywords
    brain; image reconstruction; medical image processing; positron emission tomography; readout electronics; solid scintillation detectors; APD array; ASIC system; LSO crystal detector; RatCAP conscious small animal PET tomograph; VME readout system; brain; image reconstruction; neurological activities; Anesthesia; Animal behavior; Application specific integrated circuits; Crystals; Detectors; Head; Positron emission tomography; Rats; Sensor arrays; System testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nuclear Science Symposium Conference Record, 2004 IEEE
  • ISSN
    1082-3654
  • Print_ISBN
    0-7803-8700-7
  • Type

    conf

  • DOI
    10.1109/NSSMIC.2004.1462725
  • Filename
    1462725