DocumentCode
438106
Title
The RatCAP conscious small animal PET tomograph
Author
Woody, C. ; Dzhordzhadze, V. ; Fontaine, R. ; Junnakar, S. ; Kandasamy, A. ; Kriplani, A. ; Krishnamoorthy, S. ; Lecomte, R. ; Connor, P.O. ; Page, C. ; Pratte, J.-F. ; Purschke, M. ; Radeka, V. ; Rampil, I. ; Schlyer, D. ; Shokouhi, S. ; Southekal, S. ;
Author_Institution
Brookhaven Nat. Lab., Upton, NY, USA
Volume
4
fYear
2004
fDate
16-22 Oct. 2004
Firstpage
2334
Abstract
The RatCAP is a small, head mounted PET tomograph being designed and built to image the brain of an awake rat. It will allow PET imaging studies to be carried out on la bora ton rats without the use of anesthesia, which severely suppresses brain functions and affects many of the neurological activities that one would like to study using PET. In addition, it will allow the study of animal behavior while simultaneously acquiring PET data. The tomograph consists of a 4 cm diameter ring containing 12 block detectors, each of which is comprised of a 4×8 array of 2.2×2.2×5 mm3 LSO crystals read out with a matching APD array. The APDs are read out using a custom designed ASIC and VME readout system. Most of the detector components for the RatCAP have been received and the final detector is now under construction. This paper summarizes the status of the project and gives results on detector component testing and performance, development of the readout system, results on image reconstruction, and studies on animal behavior while wearing the ring.
Keywords
brain; image reconstruction; medical image processing; positron emission tomography; readout electronics; solid scintillation detectors; APD array; ASIC system; LSO crystal detector; RatCAP conscious small animal PET tomograph; VME readout system; brain; image reconstruction; neurological activities; Anesthesia; Animal behavior; Application specific integrated circuits; Crystals; Detectors; Head; Positron emission tomography; Rats; Sensor arrays; System testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Nuclear Science Symposium Conference Record, 2004 IEEE
ISSN
1082-3654
Print_ISBN
0-7803-8700-7
Type
conf
DOI
10.1109/NSSMIC.2004.1462725
Filename
1462725
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