An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring

Author

Yen-Po Chen ; Dongsuk Jeon ; Yoonmyung Lee ; Yejoong Kim ; Zhiyoong Foo ; Inhee Lee ; Langhals, Nicholas B. ; Kruger, Grant ; Oral, Hakan ; Berenfeld, Omer ; Zhengya Zhang ; Blaauw, D. ; Sylvester, Dennis

Author_Institution

Univ. of Michigan, Ann Arbor, MI, USA

Volume

50

Issue

1

fYear

2015

fDate

Jan. 2015

Firstpage

375

Lastpage

390

Abstract

A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.

Keywords

CMOS digital integrated circuits; biomedical electronics; electrocardiography; mixed analogue-digital integrated circuits; patient monitoring; system-on-chip; AFE; CMOS process; ECG simulator; analog front-end; arrhythmia monitoring; atrial fibrillation arrhythmia detection; circuit techniques; current 31 nA; digital back-end; digital energy consumption; injectable ECG mixed-signal SoC; irregular waveform; isolated sheep heart; live sheep; minimum energy computation approach; noise optimization; power 64 nW; size 65 nm; syringe-implantable electrocardiography monitoring system; Electrocardiography; Electrodes; Gain; Heart; Impedance; Monitoring; Noise; Analog front-end (AFE); asynchronous logic; capacitive feedback chopper stabilized instrumental amplifier (CCIA); electrocardiography (ECG); fast Fourier transform (FFT); implantable system; kickback noise; minimum energy point (MEP); mm$^{3}$ ;

fLanguage

English

Journal_Title

Solid-State Circuits, IEEE Journal of

Publisher

ieee

ISSN

0018-9200

Type

jour

DOI

10.1109/JSSC.2014.2364036

Filename

6957602