Synthetic biology: from bacteria to stem cells

Synthetic biology is revolutionizing how we conceptualize and approach the engineering of biological systems. Recent advances in the field are allowing us to expand beyond the construction and analysis of small gene networks towards the implementation of complex multicellular systems with a variety of applications. We have developed an integrated computational/experimental approach to engineering complex behavior in living systems ranging from bacteria to stem cells. In our research, we appropriate useful design principles from electrical engineering and other well established fields. These principles include abstraction, standardization, modularity, and computer aided design. But we also spend considerable effort towards understanding what makes synthetic biology different from all other existing engineering disciplines and discovering new design and construction rules that are effective for this unique discipline.