Validation of GATE Monte Carlo simulation of the performance characteristics of a GE eXplore VISTA small animal PET system

Author

Yang, C.C. ; Seidel, J. ; Wang, Y. ; Lee, J.S. ; Pomper, M.G. ; Tsui, B.M.W.

Author_Institution

Nat. Yang-Ming Univ., Taipei

Volume

4

fYear

2007

fDate

Oct. 26 2007-Nov. 3 2007

Firstpage

3187

Lastpage

3190

Abstract

In this work, we validate the application of GATE (Geant4 Application for Tomographic Emission) Monte Carlo simulation software to model a GE eXplore VISTA small animal PET system. GATE was used to build our three-dimensional PET simulation model. The simulated acquired data were stored in a list-mode file and processed by the same reconstruction scheme as that used in real scanner. To validate the simulation results, several phantoms used in performance assessment experiments were modeled for simulating the system sensitivity, spatial resolution, scatter fraction and count rate response. A realistic voxelized mouse phantom was applied to present the overall quality of our model and compared with mouse images obtained from real exam.

Keywords

Monte Carlo methods; image reconstruction; image resolution; medical image processing; phantoms; positron emission tomography; 3-D PET simulation model; GATE Monte Carlo simulation software; GE eXplore VISTA; Geant4 application for tomographic emission; count rate response; quantitative small animal PET imaging technique; realistic voxelized mouse phantom; scatter fraction calculation; spatial resolution; Animals; Application software; Detectors; Event detection; Image reconstruction; Imaging phantoms; Mice; Photonic crystals; Positron emission tomography; Solid modeling;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2007. NSS '07. IEEE

Conference_Location

Honolulu, HI

ISSN

1095-7863

Print_ISBN

978-1-4244-0922-8

Electronic_ISBN

1095-7863

Type

conf

DOI

10.1109/NSSMIC.2007.4436803

Filename

4436803