Title :
Modeling Hippocampal Nonlinear Dynamic Transformations with Principal Dynamic Modes
Author :
Courellis, Spiros H. ; Zanos, Theodoros P. ; Hsiao, Min Chi ; Hampson, Robert E. ; Deadwyler, Sam A. ; Marmarelis, Vasilis Z. ; Berger, Theodore W.
Author_Institution :
Biomed. Eng. Dept., Univ. of Southern California, Los Angeles, CA
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
A new modeling approach of hippocampal nonlinear dynamics is presented. It is based on Principal Dynamics Modes (PDMs) derived from the Volterra kernels quantifying the hippocampal transformations. The approach is illustrated using data obtained from acute hippocampal slice preparations and from behaving rats performs a memory task. The resulting PDM models are comparable in performance to the Volterra models and require significantly less representational and implementational overhead
Keywords :
Volterra equations; brain models; neurophysiology; Volterra kernels; acute hippocampal slice preparation; hippocampal nonlinear dynamic model; hippocampal transformation; memory task; principal dynamic modes; Biomedical engineering; Cities and towns; Kernel; Mathematical model; Nonlinear dynamical systems; Nonlinear equations; Physiology; Rats; USA Councils; Viterbi algorithm;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260271
