Title :
A Clinical Procedure for Case-Specific Analytical Validation of Mono-Modality Image Fusion in Image Guided Radiotherapy
Author :
Hanley, Joseph ; Barbiere, Joseph ; Song, Yulin
Author_Institution :
Dept. of Radiat. Oncology, Hackensack Univ. Med. Center, NJ
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
Image guided radiotherapy can be performed by fusing the daily treatment and reference planning computed tomography scans. Decreased errors in patient setup can lead to smaller target margins that significantly improve treatment efficacy and outcome. The purpose of this work is to present a clinical procedure to analytically compute the accuracy of the registration. Accepted techniques such as normalized mutual information intensity based three-dimensional image registration can be validated using a large automated point sample. Without a user independent metric it is not possible to determine effect of the fusion error on the calculated correction in patient setup
Keywords :
computerised tomography; image fusion; image registration; medical image processing; radiation therapy; automated point sample; case-specific analytical validation; computed tomography scans; fusion error; image guided radiotherapy; mono modality image fusion; normalized mutual information intensity; three-dimensional image registration; treatment efficacy; user independent metric; Algorithm design and analysis; Biomedical imaging; Computed tomography; Image analysis; Image fusion; Medical diagnostic imaging; Medical treatment; Mutual information; Oncology; USA Councils;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.259402
