Title :
Assessment of neuro-cardiovascular uncoupling in acute brain injury patients
Author :
Papaioannou, BP ; Giannakou, MG ; Maglaveras, NM ; Sofianos, ES ; Giala, MG
Author_Institution :
Intensive Care Unit, AHEPA Teaching Hosp., Thessaloniki
Abstract :
Acute brain injury results in decreased heart rate variability (HRV) and baroreflex function. The aim of the study was a longitudinal investigation of heart rate dynamics and relation with the severity of neurological dysfunction and outcome. Metrics used were performed in 20 consecutive brain injured patients and included power spectral analysis, approximate entropy (ApEn) and transfer function (TF), as a measure of baroreflex sensitivity. There was no significant difference between survivors with different Glasgow Outcome Score (GOS = 2-5), while the six non-survivors (brain dead) with GOS = 1 had decreased variability, ApEn and TF values in relation with survivors. Mean and minimum values of different frequency components of the power spectrum were significantly associated with survival.
Keywords :
brain; cardiovascular system; entropy; haemodynamics; neurophysiology; acute brain injury; approximate entropy; baroreflex function; heart rate variability; neuro-cardiovascular uncoupling; power spectral analysis; transfer function; Baroreflex; Brain injuries; Entropy; Frequency; Heart rate; Heart rate variability; Performance evaluation; Power measurement; Spectral analysis; Transfer functions;
Conference_Titel :
Computers in Cardiology, 2006
Conference_Location :
Valencia
Print_ISBN :
978-1-4244-2532-7