Title :
Imaging fluorescence resonance energy transfer in scattering media using optical diffusion tomography
Author :
Gaind, V. ; Webb, K.J. ; Kularatne, S. ; Bouman, C.A.
Author_Institution :
Sch. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN, USA
Abstract :
We present experiments and simulations that show the microscopic fluorescence resonance energy transfer (FRET) donor-acceptor distance can be determined using a diffusion model. The approach could lead to deep tissue in-vivo FRET imaging.
Keywords :
bio-optics; biomedical optical imaging; fluorescence; optical tomography; FRET donor-acceptor distance; deep tissue in-vivo FRET imaging; imaging fluorescence resonance energy transfer; microscopic fluorescence resonance energy transfer; optical diffusion tomography; scattering media; Energy exchange; Fluorescence; Frequency modulation; Image reconstruction; Light scattering; Optical imaging; Optical scattering; Particle scattering; Resonance; Tomography; 100.3190; 170.3660; 170.3880;
Conference_Titel :
Lasers and Electro-Optics, 2009 and 2009 Conference on Quantum electronics and Laser Science Conference. CLEO/QELS 2009. Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-55752-869-8
Electronic_ISBN :
978-1-55752-869-8
