Cellular interaction with Si- and iron-based nanoparticles for bio-imaging: A study of biocompatibility

Author

Rivolta ; Amato, R.D. ; Alexandrescu, R. ; Falconieri, M. ; Morjan, I. ; Chanana, M. ; Bouzas, V. ; Costo, R. ; Fabbr, F. ; Fleacé, C. ; Garcia, M.A. ; Gasco, P. ; Gonzalez, W. ; Morales, M.P. ; Nie, Y. ; Riccio, G. ; Robic, C. ; Sancini, G. ; Vivenza, N.

Author_Institution

DIMS, Univ. of Milano-Bicocca, Milan, Italy

fYear

2009

fDate

26-30 July 2009

Firstpage

593

Lastpage

596

Abstract

The overall objective of BONSAI project (FP6, EC) is the development of ultrasensitive bio-imaging techniques based on novel multifunctional nanoparticles (NPs) with tailored optical and magnetic properties for visualizing complex cellular structures (in tissues and organs), receptors, tumour cells and masses. An important aspect to take into consideration involves the cellular responses to the impact of exogenous structures represented by NPs themselves. As a preliminary sign of reaction, we start to investigate the basic cytotoxicity.

Keywords

biological organs; biological tissues; biomedical imaging; biomedical materials; cellular biophysics; iron compounds; nanobiotechnology; nanoparticles; silicon compounds; tumours; BONSAI project; bio-imaging; bio-imaging techniques; biological organs; cellular interaction; complex cellular structures; cytotoxicity; exogenous structures; iron-based nanoparticles; multifunctional nanoparticles; receptors; tissues; tumour cells; Biomedical optical imaging; Gas lasers; Iron; Magnetic resonance imaging; Nanoparticles; Optical sensors; Production; Silicon; Tumors; Visualization;

fLanguage

English

Publisher

ieee

Conference_Titel

Nanotechnology, 2009. IEEE-NANO 2009. 9th IEEE Conference on

Conference_Location

Genoa

ISSN

1944-9399

Print_ISBN

978-1-4244-4832-6

Electronic_ISBN

1944-9399

Type

conf

Filename

5394763