Title :
Label-free measurement of DNA oligomer binding using a highly-sensitive photonic crystal biosensor
Author :
Guo, Yunbo ; Ye, Jing Yong ; Thomas, Thommey P. ; Baker, James R., Jr. ; Norris, Theodore B.
Abstract :
With a highly sensitive one dimensional photonic crystal biosensor, we have demonstrated quantitative real-time label-free detection of DNA oligomers, including binding to protein, concentration detection limits, and base-mismatched hybridization.
Keywords :
Biomedical measurements; Biomedical optical imaging; Biosensors; DNA; Optical interferometry; Optical sensors; Optical surface waves; Photonic crystals; Resonance; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics (CLEO) and Quantum Electronics and Laser Science Conference (QELS), 2010 Conference on
Conference_Location :
San Jose, CA, USA
Print_ISBN :
978-1-55752-890-2
Electronic_ISBN :
978-1-55752-890-2
