Effect of blood vessel locations on HIFU temperature field: A simulation study

Author

Zhang, Ping ; Sun, Wujun ; Zhu, Yuanguang ; Zhang, Xiaojing ; Zhang, Mizuo ; Jian, Xiqi

Author_Institution

Sch. of Biomed. Eng., Tianjin Med. Univ., Tianjin, China

Volume

3

fYear

2010

fDate

16-18 Oct. 2010

Firstpage

1162

Lastpage

1165

Abstract

A 3-D numerical model is presented to study the effect of blood vessel locations on high intensity focused ultrasound (HIFU) temperature field. The model is based on the Westervelt formula and Pennes bio-heat transfer equation. The finite difference time domain (FDTD) method is used to obtain the temperature distribution induced by HIFU procedures. Temperature rise and focal area are then shown for different locations of blood vessel. Results show that when the blood vessel is located on the ultrasound beam, significant reduction in temperature rise is observed due to blood flow. If there is a gap between the beam axis and blood vessel, the latter part of focal region is no longer symmetric. It exists a negligible change in the peak temperature rise for gap=1.0mm or gap=3.0mm, compared with no blood model.

Keywords

biomedical ultrasonics; biothermics; biotransport; blood vessels; finite difference time-domain analysis; haemodynamics; heat transfer; radiation therapy; temperature distribution; 3D numerical model; HIFU temperature field; Pennes bio-heat transfer equation; Westervelt formula; blood flow; blood vessel locations; finite difference time domain method; focal area; high intensity focused ultrasound; temperature distribution; temperature rise; Acoustic beams; Biological system modeling; Blood; Mathematical model; Numerical models; Ultrasonic imaging; FDTD; HIFU; blood vessel locations; focal region;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics (BMEI), 2010 3rd International Conference on

Conference_Location

Yantai

Print_ISBN

978-1-4244-6495-1

Type

conf

DOI

10.1109/BMEI.2010.5639596

Filename

5639596