Self-excited oscillation device of lipid across a micropore and its dynamic behavior

Author

Sha, Seimei ; Moriizumi, Toyosaka

Author_Institution

Dept. of Electr. Eng., Tokyo Inst. of Technol., Tokyo, Japan

Volume

1

fYear

1992

fDate

Oct. 29 1992-Nov. 1 1992

Firstpage

196

Lastpage

197

Abstract

A rhythmic, sustained, stable potential oscillation was reproducibly observed for a lipid membrane supported by a micropore of a thin membrane tip micropipette. Amplitude and period of the oscillation voltage was controlled by changing the pore diameter. In order to clarify the mechanism, the dynamic behavior of a lipid across a micropore during the self-excited potential oscillation phenomenon was observed by an optical microscope. The potential change during self-excited oscillation was quite synchronous with the expansion and shrinkage of the domelike lipid aggregate formed in tin water phase.

Keywords

aggregates (materials); bioelectric potentials; biological techniques; biomembranes; cellular biophysics; lipid bilayers; optical microscopy; oscillations; domelike lipid aggregate; dynamic behavior; lipid; lipid membrane; micropore; optical microscope; oscillation voltage; pore diameter; rhythmic sustained stable potential oscillation; self-excited oscillation device; self-excited potential oscillation; thin membrane tip micropipette; Biomembranes; Electric potential; Fitting; Lipidomics; Microscopy; Optical microscopy; Oscillators;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1992 14th Annual International Conference of the IEEE

Conference_Location

Paris

Print_ISBN

0-7803-0785-2

Electronic_ISBN

0-7803-0816-6

Type

conf

DOI

10.1109/IEMBS.1992.5760923

Filename

5760923