Title :
3D optical coherence tomography (OCT) — An investigation of intimal-medial thickness (IMT) and Wall Shear Stress (WSS) in a patient´s coronary artery
Author :
Suo, Jin ; McDaniel, Michael ; Eshtehardi, Parham ; Dhawan, Saurabh S. ; Taylor, Robert W. ; Samady, Habib ; Giddens, Don P.
Author_Institution :
Wallace H. Coulter Dept. of Biomed. Eng., Georgia Tech & Emory Univ., Atlanta, GA, USA
Abstract :
Current OCT presents only two-dimensional (2D) slices, which limit the spatial information available. We have developed three-dimensional (3D) OCT methodology by combining OCT with biplane angiography, allowing reconstruction of a realistic lumen of coronary arteries with higher local resolution than by other methods, e.g. intravascular ultrasound (IVUS). Intimal-medial thickening (IMT) in the left anterior descending (LAD) coronary artery of a patient were investigated by OCT and IVUS. An inverse relationship between WSS obtained through computational fluid dynamics (CFD) and IMT as determined from the intravascular imaging techniques was found. The relationship is consistent with previous results from autopsy studies.
Keywords :
angiocardiography; biomedical ultrasonics; blood vessels; computational fluid dynamics; image reconstruction; image resolution; medical image processing; optical tomography; shear strength; 2D slices; 3D OCT; 3D optical coherence tomography; CFD; IMT; IVUS; WSS; autopsy study; biplane angiography; computational fluid dynamics; coronary artery reconstruction; intimal-medial thickening; intimal-medial thickness; intravascular imaging techniques; intravascular ultrasound; left anterior descending coronary artery; local resolution; patient LAD coronary artery; patient coronary artery; realistic lumen; spatial information; three-dimensional OCT methodology; two-dimensional slices; wall shear stress; Arteries; Computational fluid dynamics; Educational institutions; Image color analysis; Image reconstruction; Imaging; Three dimensional displays;
Conference_Titel :
Computing in Cardiology, 2011
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4577-0612-7
