DocumentCode :
56533
Title :
Predicting Outcomes of Nonsmall Cell Lung Cancer Using CT Image Features
Author :
Hawkins, Samuel H. ; Korecki, John N. ; Balagurunathan, Yoganand ; Yuhua Gu ; Kumar, Virendra ; Basu, Satrajit ; Hall, Lawrence O. ; Goldgof, Dmitry B. ; Gatenby, Robert A. ; Gillies, Robert J.
Author_Institution :
Dept. of Comput. Sci. & Eng., Univ. of South Florida, Tampa, FL, USA
Volume :
2
fYear :
2014
fDate :
2014
Firstpage :
1418
Lastpage :
1426
Abstract :
Nonsmall cell lung cancer is a prevalent disease. It is diagnosed and treated with the help of computed tomography (CT) scans. In this paper, we apply radiomics to select 3-D features from CT images of the lung toward providing prognostic information. Focusing on cases of the adenocarcinoma nonsmall cell lung cancer tumor subtype from a larger data set, we show that classifiers can be built to predict survival time. This is the first known result to make such predictions from CT scans of lung cancer. We compare classifiers and feature selection approaches. The best accuracy when predicting survival was 77.5% using a decision tree in a leave-one-out cross validation and was obtained after selecting five features per fold from 219.
Keywords :
cancer; cellular biophysics; computerised tomography; diseases; feature selection; image classification; lung; medical image processing; 3D feature selection; CT image features; adenocarcinoma nonsmall cell lung cancer tumor subtype; computed tomography; decision tree; disease; prognostic information; radiomics; Biomedical image processing; Cancer; Cells (biology); Computed tomography; Diseases; Lung cancer; Support vector machines; Three-dimensional displays; Tumors; CT 3D texture features; Computed tomography; Naive Bayes; decision tree; support vector machine;
fLanguage :
English
Journal_Title :
Access, IEEE
Publisher :
ieee
ISSN :
2169-3536
Type :
jour
DOI :
10.1109/ACCESS.2014.2373335
Filename :
6966732
Link To Document :
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