Title :
Modularity and centrality in an sRNA network
Author :
Long, Ying ; Dewu, Ding
Author_Institution :
Educ. Dept., Nat. Univ. of Defense Technol., Changsha, China
Abstract :
Small RNAs (sRNAs) are small, non-coding RNA species that control numerous cellular processes, and they are important components of post-transcriptional regulation. We study an sRNA network in the present paper, emphasis has been focused on modularity and centrality in the sRNA network. We engage a link clustering method for analyzing the sRNA network, and identify biologically functional modules and key genes in the sRNA network.
Keywords :
RNA; biology computing; cellular biophysics; genetics; biologically functional module; cellular process; centrality; link clustering method; modularity; noncoding RNA species; post-transcriptional regulation; sRNA network; small RNA; Analytical models; Biological system modeling; Clustering methods; Complex networks; Proteins; RNA; biological networks; centrality; modularity; systems biology;
Conference_Titel :
Control Conference (CCC), 2012 31st Chinese
Conference_Location :
Hefei
Print_ISBN :
978-1-4673-2581-3
