Title :
Study of split-ring resonators for use on a pharmaceutical drug capsule for microwave activated drug release
Author :
Jonasson, Scevar Por ; Jensen, Brian Sveistrup ; Johansen, Tom K.
Author_Institution :
Dept. of Electr. Eng., Tech. Univ. of Denmark, Lyngby, Denmark
fDate :
Oct. 29 2012-Nov. 1 2012
Abstract :
In this paper, a novel method for externally activating a pharmaceutical drug capsule by use of split-ring resonators (SRR) is introduced. To this end, the effect of the orientation of the SRRs on the ability to activate the capsules is examined. A coplanar waveguide is used to excite an identical pair of SRRs fabricated on a substrate, representing an enlarged lid for a pharmaceutical drug capsule. Orientations where the electric field component of a quasi-TEM wave lies across the gap of the SRRs provides the largest response. The optimal case is when the electric field component lies across the gap simultaneously with the magnetic field component normal to the SRRs. Furthermore, an analysis of the optimal conductivity and relative permittivity for enhanced temperature rise in the lid is performed. Conductivity of 0.09 S/m and relative permittivity of 12 shows the highest temperature rise.
Keywords :
bioelectric potentials; coplanar waveguides; drug delivery systems; drugs; electrical conductivity; microwave resonators; permittivity; transmission electron microscopy; coplanar waveguide; electric field component; magnetic field component; microwave activated drug release; optimal conductivity; pharmaceutical drug capsule; quasiTEM; relative permittivity; split-ring resonators; transmission electron microscopy; Conductivity; Coplanar waveguides; Drugs; Electromagnetic heating; Permittivity; Substrates; Split-ring resonator; drug activation; drug delivery; drug release;
Conference_Titel :
Microwave Conference (EuMC), 2012 42nd European
Conference_Location :
Amsterdam
Print_ISBN :
978-1-4673-2215-7
Electronic_ISBN :
978-2-87487-026-2