Mri of spio-labeled mesenchymal stem cells in an animal model of acute renal failure at a clinical 3T system

Author

Ittrich, H. ; Lange, C. ; Toegel, F. ; Zander, A.R. ; Westenfelder, C. ; Adam, Grain ; Nolte-Ernsting, C.

Author_Institution

Dept. of Diagnostic & Interventional Radiol., Univ. Med. Center Hamburg-Eppendorf, Hamburg, Germany

fYear

2013

fDate

23-24 March 2013

Firstpage

1

Lastpage

1

Abstract

Optimized methods in MRI allow for qualitative and quantitative in-vivo cell-tracking and monitoring of organ distribution of SPIO-labeled MSC in clinical acute renal failure (ARF) in rate at a clinical 3T MR system. The study demonstrates the potential of in-vivo MRI for qualitative tracking and quantification of SPIO-labeled stem cells in future therapeutic treatment protocols.

Keywords

biomedical MRI; cellular biophysics; diseases; iron compounds; kidney; Fe₂O₃; SPIO-labeled MSC; SPIO-labeled mesenchymal stem cells; animal model; clinical MR system; clinical acute renal failure; in-vivo MRI; in-vivo cell-tracking; magnetic flux density 3 T; organ distribution; superparamagnetic iron oxide; Animals; Bones; Educational institutions; Kidney; Magnetic resonance imaging; Signal to noise ratio; Stem cells;

fLanguage

English

Publisher

ieee

Conference_Titel

Magnetic Particle Imaging (IWMPI), 2013 International Workshop on

Conference_Location

Berkeley, CA

Print_ISBN

978-1-4673-5520-9

Electronic_ISBN

978-1-4673-5521-6

Type

conf

DOI

10.1109/IWMPI.2013.6528362

Filename

6528362