Magnetic nanotherapeutics of Guerin carcinoma

Author

Orel, V.E. ; Nikolov, N.A. ; Rykhalskiy, A.Y. ; Dzyatkovskya, N.N. ; Romanov, A.V. ; Yaroshenko, O.Yu. ; Supruniuk, D. ; Orel, V.B. ; Khamrovskiy, M.M. ; Penievskyi, M.I. ; Radaguz, A.V.

Author_Institution

Med. Phys. & Bioeng. Dept., Nat. Cancer Inst., Kiev, Ukraine

fYear

2013

fDate

16-19 April 2013

Firstpage

241

Lastpage

245

Abstract

The research of animals with Guerin carcinoma has shown, that magneto-mechano-chemically synthesized magnetic nanocomplex on the basis of Fe₃O₄ nanoparticles with antitumor anthracycline row antibiotic doxorubicin and next local electromagnetic irradiation by spatially inhomogeneous constant magnetic and variable electromagnetic fields had a greater antitumor effect than conventional doxorubicin and magnetomechano-chemically synthesized magnetic nanocomplex without electromagnetic irradiation.

Keywords

biological effects of fields; biomagnetism; cancer; drugs; iron compounds; magnetic particles; nanomedicine; nanoparticles; tumours; Fe₃O₄; Fe₃O₄ nanoparticles; Guerin carcinoma; antitumor anthracycline row antibiotic doxorubicin; antitumor effect; conventional doxorubicin; local electromagnetic irradiation; magnetic nanotherapeutics; magneto-mechano-chemically synthesized magnetic nanocomplex; spatially inhomogeneous constant magnetic fields; variable electromagnetic fields; Magnetic flux; Magnetic separation; Magnetomechanical effects; Magnetostatics; Saturation magnetization; Tumors; electromagnetic field; magnetic nanocomplex; magnetic-dipole applicator; tumor;

fLanguage

English

Publisher

ieee

Conference_Titel

Electronics and Nanotechnology (ELNANO), 2013 IEEE XXXIII International Scientific Conference

Conference_Location

Kiev

Print_ISBN

978-1-4673-4669-6

Type

conf

DOI

10.1109/ELNANO.2013.6552027

Filename

6552027