DocumentCode :
627984
Title :
Delivery of Anti-Cancer Drugs Using Nanocarriers
Author :
Lally, Beth ; Gettens, R. ; Sani, Shabnam
Author_Institution :
Dept. of Biomed. Eng., Western New England Univ., Springfield, MA, USA
fYear :
2013
fDate :
5-7 April 2013
Firstpage :
261
Lastpage :
262
Abstract :
The most prevalent form of cancer treatment used today is chemotherapy, although it is widely known to be associated with frequent, high dosages and unwanted side effects. The application of nanocarriers to conventional cancer treatment aims to address these problems by encapsulating chemotherapeutic drugs within polymer or lipid nanoparticles. These drug delivery nanoparticles, known as nanocarriers, work to increase the stability and circulation time of drugs and can be used to target specific areas. This project aims to fabricate nanocarriers for the delivery of chemotherapeutic drugs in order to address the current problems of chemotherapy. These nanocarriers will reduce side effects and issues of conventional dosage forms by targeting tumor sites, releasing drug specifically and only where it is needed.
Keywords :
biomedical materials; cancer; dosimetry; drug delivery systems; drugs; encapsulation; lipid bilayers; nanofabrication; nanomedicine; nanoparticles; polymers; tumours; anticancer drug delivery; chemotherapeutic drug encapsulation; conventional cancer treatment; conventional dosage forms; drug circulation time; drug delivery nanoparticles; drug stability; lipid nanoparticles; nanocarriers; polymer nanoparticles; tumor sites; Cancer; Chemotherapy; Drug delivery; Drugs; Fabrication; Materials; Safety; PEG-PE; PLGA; emulsification-diffusion; lipid film hydration; nanocarriers; passive targeting;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bioengineering Conference (NEBEC), 2013 39th Annual Northeast
Conference_Location :
Syracuse, NY
ISSN :
2160-7001
Print_ISBN :
978-1-4673-4928-4
Type :
conf
DOI :
10.1109/NEBEC.2013.74
Filename :
6574458
Link To Document :
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