Fully automated calcium detection using optical coherence tomography

Author

Athanasiou, Lambros S. ; Bourantas, C.V. ; Rigas, George A. ; Exarchos, Themis P. ; Sakellarios, Antonios I. ; Siogkas, Panagiotis K. ; Papafaklis, Michail I. ; Naka, Katerina K. ; Michalis, Lampros K. ; Prati, F. ; Fotiadis, Dimitrios I.

Author_Institution

Dept. of Mater. Sci. & Eng., Univ. of Ioannina, Ioannina, Greece

fYear

2013

fDate

3-7 July 2013

Firstpage

1430

Lastpage

1433

Abstract

Optical Coherence Tomography (OCT) is a new invasive technology for performing high-resolution cross-sectional imaging of the coronary arteries. In OCT images only Calcified plaque (CA) components can be accurately depicted as light penetrates hard tissue. In this work we present an automated method for detecting CA in OCT images. The method is fully automated as no user intervention is needed and includes three steps. In the first step the region between the lumen and the maximum penetration depth of OCT from the lumen border is determined. In the second step the region is classified into 3 clusters using the K-means algorithm. CA is identified using the results of k-means. The method was validated using expeerts´ annotations on 27 images. The sensitivity of the method is 83% with Positive predictive value (PVV) 74 %.

Keywords

biomedical optical imaging; blood vessels; calcium; diseases; image classification; image resolution; medical image processing; optical tomography; K-means algorithm; OCT images; calcified plaque components; clusters classification; coronary arteries; experts annotations; fully automated calcium detection; hard tissue; high-resolution cross-sectional imaging; invasive technology; light penetration; lumen border; maximum penetration depth; optical coherence tomography; positive predictive value; sensitivity; Calcium; Catheters; Coherence; Optical imaging; Optical sensors; Sensitivity; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE

Conference_Location

Osaka

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2013.6609779

Filename

6609779