DocumentCode
636728
Title
Assessment of spectral bands of interest in airflow signal to assist in sleep apnea-hypopnea syndrome diagnosis
Author
Gutierrez-Tobal, Gonzalo C. ; Alvarez, Daniel ; Gomez, Jose ; del Campo, Felix ; Hornero, Roberto
Author_Institution
Biomed. Eng. Group, Univ. of Valladolid, Valladolid, Spain
fYear
2013
fDate
3-7 July 2013
Firstpage
5021
Lastpage
5024
Abstract
In this work, we analyze power spectral density (PSD) from single-channel airflow (AF) in the context of sleep apnea-hypopnea syndrome (SAHS) diagnosis. PSDs from SAHS-positive and SAHS-negative subjects were compared through Mann-Whitney test to find bands of interest. Thereby, we characterized three spectral bands (BW1-BW3) by their relative power (PR1-PR3) and established relationships with apneas and hypopneas. Then, the single and joint diagnostic ability of PR1-PR3 was assessed by means of K-nearest neighbours (KNN), Fisher´s linear discriminant (FLD), and logistic regression (LR) classifiers. The KNN and LR models, obtained from PR1-PR3, showed the best diagnostic ability after a leave-one-out cross-validation procedure. 87.7%-84.2% accuracy and 0.799-0.853 area under receiver operating characteristics curve (AROC) were achieved, respectively. Our results suggest that the bands of interest we defined are related to apneas and hypopneas and, therefore, can be useful in SAHS diagnosis.
Keywords
diseases; medical signal processing; patient diagnosis; regression analysis; sensitivity analysis; statistical testing; AROC; Fisher linear discriminant classifiers; K-nearest neighbours; LR models; Mann-Whitney test; SAHS diagnosis; airflow signal; area under receiver operating characteristics curve; hypopneas; leave-one-out cross-validation procedure; logistic regression classifiers; power spectral density; single-channel airflow; sleep apnea-hypopnea syndrome diagnosis; spectral band; Accuracy; Artificial intelligence; Correlation; Indexes; Logistics; Sleep apnea;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location
Osaka
ISSN
1557-170X
Type
conf
DOI
10.1109/EMBC.2013.6610676
Filename
6610676
Link To Document