• DocumentCode
    636728
  • Title

    Assessment of spectral bands of interest in airflow signal to assist in sleep apnea-hypopnea syndrome diagnosis

  • Author

    Gutierrez-Tobal, Gonzalo C. ; Alvarez, Daniel ; Gomez, Jose ; del Campo, Felix ; Hornero, Roberto

  • Author_Institution
    Biomed. Eng. Group, Univ. of Valladolid, Valladolid, Spain
  • fYear
    2013
  • fDate
    3-7 July 2013
  • Firstpage
    5021
  • Lastpage
    5024
  • Abstract
    In this work, we analyze power spectral density (PSD) from single-channel airflow (AF) in the context of sleep apnea-hypopnea syndrome (SAHS) diagnosis. PSDs from SAHS-positive and SAHS-negative subjects were compared through Mann-Whitney test to find bands of interest. Thereby, we characterized three spectral bands (BW1-BW3) by their relative power (PR1-PR3) and established relationships with apneas and hypopneas. Then, the single and joint diagnostic ability of PR1-PR3 was assessed by means of K-nearest neighbours (KNN), Fisher´s linear discriminant (FLD), and logistic regression (LR) classifiers. The KNN and LR models, obtained from PR1-PR3, showed the best diagnostic ability after a leave-one-out cross-validation procedure. 87.7%-84.2% accuracy and 0.799-0.853 area under receiver operating characteristics curve (AROC) were achieved, respectively. Our results suggest that the bands of interest we defined are related to apneas and hypopneas and, therefore, can be useful in SAHS diagnosis.
  • Keywords
    diseases; medical signal processing; patient diagnosis; regression analysis; sensitivity analysis; statistical testing; AROC; Fisher linear discriminant classifiers; K-nearest neighbours; LR models; Mann-Whitney test; SAHS diagnosis; airflow signal; area under receiver operating characteristics curve; hypopneas; leave-one-out cross-validation procedure; logistic regression classifiers; power spectral density; single-channel airflow; sleep apnea-hypopnea syndrome diagnosis; spectral band; Accuracy; Artificial intelligence; Correlation; Indexes; Logistics; Sleep apnea;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
  • Conference_Location
    Osaka
  • ISSN
    1557-170X
  • Type

    conf

  • DOI
    10.1109/EMBC.2013.6610676
  • Filename
    6610676